COVID-19感染对人体构成的长期影响
Ornina Atieh1, Jared C Durieux2, Jhony Baissary1
1School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Nutrients
|May 11, 2024
概括
在COVID-19的幸存者经历了在疫情期间瘦体质的下降,与未感染的人不同. 两组都增加了脂肪,可能是由于生活方式的改变,但只有幸存者显示瘦身量减少.
科学领域:
- 人类生理学 人类生理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- COVID-19 感染和流行病相关的生活方式改变对人体构成的影响尚未完全理解.
- 这项研究比较了COVID-19幸存者的长期身体成分变化与对照组.
研究的目的:
- 为了调查 COVID-19 幸存者与没有幸存者之间的长期身体组成变化.
- 为了区分直接的COVID-19感染与间接的流行病影响对身体指标的影响.
主要方法:
- 对患有大流行前 (2017-2019) 和大流行后DXA扫描的成年人进行前性研究.
- 收集的数据包括病史,COVID-19状态,炎症标志物和禁食脂质.
- 对于COVID-19幸存者,DXA扫描的时间是感染后至少一年.
主要成果:
- 160名成年人参加:女性32.5%,非白人51.8%,平均年龄43.2岁.
- COVID-19阴性参与者表现出干脂肪,总脂肪和瘦体质量 (LBM) 的增加.
- 与对照组相比,COVID-19幸存者在脂肪质量或LBM中没有显著变化,无论PASC如何.
结论:
- 无论是COVID-19幸存者还是对照者,都增加了脂肪和体重,这可能是由于大流行改变了生活方式.
- 在研究期间,只有COVID-19幸存者在瘦身量 (LBM) 显著下降.
- 幸存者中LBM的下降发生在不考虑SARS-CoV-2 (PASC) 症状的急性后续症状的情况下.
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