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Giulio Giovannetti¹, Alessandra Flori², Nicola Martini²

¹Institute of Clinical Physiology, National Council of Research, Via G. Moruzzi 1, 56124 Pisa, Italy.

Sensors (Basel, Switzerland)

|May 11, 2024

概括

-23磁共振成像 (NaMRI) 提供了超越标准质子成像的宝贵生化见解. 本研究介绍了一种标准化的硬件和软件设置,用于在临床扫描仪上可靠的NaMRI.

科学领域:

生物医学成像技术生物医学成像技术
磁共振光谱学磁共振光谱学
医学物理医学物理

背景情况:

23NaMRI提供了定量生物化学信息,扩展了MRI能力超出了解剖质子成像.
临床扫描仪面临的挑战是低Na信号和旋磁比率,需要专门的射频线圈,序列和幻影.
多核光谱 (MNS) 功能对于先进的MR应用是必需的.

研究的目的:

提出和评估一个硬件和软件设置,以评估临床扫描仪上的NaMRI的潜力.
用开发的设置来验证测量的可靠性和可重复性.
建立标准化临床和研究NaMRI协议的基础.

主要方法:

为NaMRI开发一个专用的硬件和软件设置.
使用3TMR扫描仪与自制射频 (RF) 容量线圈.
采用专门的序列和定制设计的幻影用于准确性评估.

主要成果:

使用拟议的设置证明了23NaMRI测量的可靠性和可重复性.
通过幻影成像验证了该技术的准确性.
该设置成功启用了临床MRI扫描仪上的Na成像.

结论:

拟议的硬件和软件设置可靠且可用于临床扫描仪上的NaMRI.
这项工作为在临床和研究环境中标准化NaMRI协议提供了基础.
纳米磁共振成像具有用于定量生化评估的重大潜力.

关键词:

23Na线圈的设计 23Na磁共振成像技术的使用.

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