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Updated: Jun 26, 2025

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一种小分子化合物759通过增加Axin蛋白稳定性来抑制wnt/β-catenin信号通路

Seunghan Sun1, Young-Dae Gong2, Jong Soon Kang3

  • 1School of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.

Medical oncology (Northwood, London, England)
|May 11, 2024
PubMed
概括

化合物759通过增加Axin1蛋白稳定性,抑制增殖和减少瘤生长来抑制肺癌细胞中的Wnt/β-catenin信号传递. 这种化合物显示出作为抗癌疗法的潜力.

关键词:
亚克辛 (Axin) 是一种催化剂.化合物759 是一个化合物.肺癌是一种肺癌.蛋白质的稳定性 蛋白质的稳定性治疗方法 治疗方法在Wnt/β-catenin路径中.

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