与大小解析颗粒的活性氧物种相关的氧化潜力:特定来源的重要作用
Kaixing Yao1, Yihao Xu1, Han Zheng1
1Department of Environmental Engineering, Xiamen University of Technology, Xiamen, 361024, China.
Journal of environmental management
|May 11, 2024
概括
交通排放对颗粒物 (PM) 氧化潜力和反应性氧物种 (ROS) 形成有重大影响,对人类健康构成风险. 控制这些排放,特别是在沿海地区,对于减轻PM暴露对健康的不利影响至关重要.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 大气化学 大气化学
背景情况:
- 氧化潜力 (OP) 是颗粒物 (PM) 毒性的关键指标.
- 有限的研究存在于OP和来自特定排放源的PM的毒性.
- 了解PM对活性氧物种 (ROS) 的贡献对于评估健康风险至关重要.
研究的目的:
- 来自各种来源的尺寸解析 PM 中的 OP 和 ROS 形成的特征.
- 通过沉积模型评估PM产生的OP和ROS对健康的影响.
- 确定有助于PM氧化活性的关键成分.
主要方法:
- 使用dithiothreitol (DTT) 方法分析大小解析的PM OP.
- 使用电子磁共振 (EPR) 谱学量化ROS.
- 通过多路径颗粒沉积 (MPPD) 模型进行健康影响评估.
主要成果:
- 交通来源显示出水溶性OP (OPws) 的最高值,而海洋来源显示出最低值.
- 微粒小于3.2微米 (PM<3.2) 是由于氧化活性较高而造成不良健康影响的主要原因.
- 过渡金属被确定为所有来源的PM中DTT消耗的主要贡献者.
结论:
- 交通排放是环境PM中ROS的主要来源,特别是PM<3.2.2.
- 超过66%的肺DTT损失和71%的ROS生成归因于PM<3.2.2.
- 控制交通排放,特别是在沿海地区,对于减少PM相关的健康风险至关重要.
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