相关实验视频

Updated: Jun 26, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

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一项基于多组织,拼接的联合转录基因组范围的关联研究确定了乳腺癌易感基因

Guimin Gao1, Julian McClellan1, Alvaro N Barbeira2

  • 1Department of Public Health Sciences, University of Chicago, Chicago, IL 60637, USA.

American journal of human genetics
|May 11, 2024
PubMed
概括

这项研究引入了一项多组织关节拼接转录组范围的关联研究 (拼接-TWAS),以确定乳腺癌易感基因. 与传统方法相比,这种新的方法显著提高了基因发现,突出显示了拼接定量特征位点 (sQTLs) 的重要性.

关键词:
替代性拼接是一种替代性的拼接.乳腺癌 乳腺癌 乳腺癌内脏切除术 (intron excision) 是一种内脏切除术.联合分析 联合分析多组织的多组织组织.敏感性基因是敏感性的基因.转录组范围的关联研究研究.

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