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Updated: Jun 26, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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结构性转变使得18型白蛋白的成熟和信号传递成为可能

Ying Dong1, Jeffrey P Bonin2, Pascal Devant3

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.

Immunity
|May 11, 2024
PubMed
概括

卡斯帕-1与卡斯帕-4不同地处理亲IL-18,利用其活性位点而不是外位点. 这种裂变对于激活IL-18至关重要.

关键词:
它们的IL-18型.这就是NMR的NMR.卡斯帕斯-1酶是一种形状的变化 形状的变化低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.细胞因子分离 细胞因子分裂炎症活动的炎症活动.支持IL-18的人.

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