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在CAR T细胞治疗后,免疫效应细胞相关的血液毒性:从机制到管理

Kai Rejeski1, Michael D Jain2, Nirali N Shah3

  • 1Adult BMT and Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany; Laboratory for Translational Cancer Immunology, LMU Gene Center, Munich, Germany.

The Lancet. Haematology
|May 11, 2024
PubMed
概括

化学抗原受体 (CAR) T细胞疗法可能导致显著的血液毒性 (ICAHT),需要新的分类和风险评分,如CAR-HEMATOTOX,以更好地管理患者和预防感染.

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