在西班牙,由于Listeria monocytogenes感染的发病率和死亡率增加
Elena Vázquez1, Oscar de Gregorio-Vicente1, Vicente Soriano1
1UNIR Health Sciences School and Medical Center, Madrid, Spain.
概括
从2000年到2021年,西班牙的Listeria monocytogenes (LM) 住院和死亡人数显著增加. 这种增长与人口老龄化和免疫抑制个体的增加有关,突出显示出越来越多的公共卫生问题.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生监督 公共卫生监督
- 流行病学 流行病学
背景情况:
- 由于其高死亡率,Listeria monocytogenes (LM) 对全球健康构成重大风险.
- 在全球范围内,高风险易感人群的比例,包括老年人和免疫受损者,正在增加.
研究的目的:
- 分析与西班牙的Listeria monocytogenes相关的住院和死亡率的趋势.
- 识别影响LM相关住院和住院死亡的人口统计和临床因素.
主要方法:
- 追溯分析西班牙所有被诊断为Listeria monocytogenes的住院病例.
- 数据是从2000年至2021年间的国家医院出院登记处提取的.
- 统计分析以评估趋势,死亡率和相关风险因素.
主要成果:
- 在2000年至2021年期间,发现了8152例LM入院病例,住院率显著增加.
- 住院死亡率为16.7%,死亡人数显著上升,从每10万人口中的7.8人增加到18人.
- 增加年龄 (>65岁),败血症,脑膜炎,内心炎,新生儿李斯特菌病和免疫抑制与死亡率有显著的关联.
结论:
- 在西班牙,由于Listeria monocytogenes的住院和死亡数量在过去二十年里大幅增加.
- 越来越多的老年人口和免疫抑制个体的增加是这一趋势的关键驱动因素.
- 需要有效的公共卫生策略来应对LM感染日益增加的负担.
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