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Updated: Jun 26, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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在新辅助免疫疗法后的单细胞免疫基因组学景观结合化学疗法在食道状细胞癌中的食道状细胞癌

Zheyi Wang1, Yue Zhao1, Yang Wo1

  • 1Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, Shanghai, China; Institute of Thoracic Oncology, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Cancer letters
|May 11, 2024
PubMed
概括

在食道癌症中,新辅助免疫疗法显示了丰富的效能记忆T细胞和减少响应者中耗尽的T细胞. 这表明由T和B细胞相互作用驱动的持续性抗瘤反应,改善了治疗灵敏度.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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