心脏外科手术中的心脏周流体素
Ali Fatehi Hassanabad1, Adham H El-Sherbini2, Ibrahim Ahmed Cherif2
1Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
心脏外科手术后,心脏周心液 (PF) 中心脏托罗邦素水平增加,无论手术如何. 这些升高的PF素水平高于血清水平,但它们的临床意义需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 生物化学 生物化学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 心周液 (PF) 含有生物活性因子.
- PF组成可能反映心脏间歇性变化.
- 心脏中热素是心肌损伤的关键生物标志物.
研究的目的:
- 为了确定心脏手术的患者在PF中心脏激素水平是否发生变化.
- 为了研究PF热素水平和心脏手术之间的关系.
- 为了比较手术后的PF激素水平与血清激素水平.
主要方法:
- 根据PRISMA指南进行范围审查.
- 在Medline,EMBASE,Cochrane,ClinicalTrials.gov和谷歌学者的系统搜索.
- 包括六项分析心脏手术后PF中的心脏托洛的研究.
主要成果:
- 心脏外科手术后,心脏周边热素度显著增加.
- PF中的热素水平始终高于血清中的水平.
- 心脏手术的类型没有影响观察到的PF托罗宁水平的增加.
结论:
- 心脏外科手术后心周液中热素水平上升,无论手术方法如何.
- 这些升高的PF素水平的确切模式和临床影响尚未确定.
- 需要进一步的研究来阐明心周热素变化的临床意义.
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