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Updated: Jun 26, 2025

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氨基酸作为lyszyme在喷雾干燥过程和储存过程中的稳定剂

Chengqian Zhang1, Flemming Steen Jørgensen2, Marco van de Weert1

  • 1Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.

International journal of pharmaceutics
|May 11, 2024
PubMed
概括

氨基酸在喷雾干燥过程中稳定蛋白质,但它们的有效性取决于物理化学特性和微环境pH值,而不仅仅是传统理论.

关键词:
微环境的pH值分子描述器分子描述器固体形式 固体形式稳定的稳定性 稳定的稳定性治疗性蛋白质是一种治疗蛋白质.

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相关概念视频

Amino acids03:42

Amino acids

Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible...
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