准备,结构特征和功能属性为库尔库封装的-lyszyme-κ-carrageenan三元纳米复合材料的库尔库封装
Jin Chen1, Zhuangwei Zhang2, Huihui Li1
1College of Biological and Food Engineering, Anhui Polytechnic University, Wuhu 241000, PR China.
International journal of biological macromolecules
|May 11, 2024
概括
研究人员开发了简酶-κ-卡拉基南复合纳米复合物 (ZLKC) 来改善黄素的输送. 这些ZLKC纳米粒子有效地封装黄素,提高其稳定性和生物可用性,用于潜在的食品和医疗应用.
科学领域:
- 食品科学 食品科学 食品科学
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 黄素具有较差的水溶性和生物可用性,限制了其在食品和医药中的使用.
- 基于扎因酶的纳米材料显示出潜力,但需要进一步描述功能应用.
研究的目的:
- 开发新型的素-酶-κ-素复合纳米复合材料 (ZLKC) 进行有效的黄素封装.
- 研究开发的ZLKC纳米粒子的物理化学特性和功能能力.
主要方法:
- 制造简-利索酶-κ-卡拉基南复合纳米复合材料 (ZLKC).
- 使用富里埃变换红外线,光谱学,解离试验,圆形二极化和X射线衍射进行表征.
- 评估封装效率,物理化学稳定性,抗氧化和抗菌性质以及释放动力学.
主要成果:
- ZLKC纳米粒子表现出光滑的球形纳米结构,具有高封装效率.
- 疏水性,静电相互作用和键是复合材料稳定性的关键.
- 封装的黄素在ZLKC纳米颗粒中缺乏结晶性.
- 添加 κ-carrageenan 增强了物理化学稳定性,并证明持续释放黄素.
- ZLKC纳米复合材料显示出改善的抗氧化和抗微生物活性.
结论:
- ZLKC纳米复合材料是黄素封装的有效载体,解决了溶解性和生物可用性问题.
- 开发的纳米复合材料系统为生物活性物质提供增强的稳定性和功能性质.
- ZLKC纳米复合材料显示出在食品和制药行业应用的巨大潜力.
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