影响糖尿病酸性糖尿病严重程度的临床变量
Yara F Alhamdani1, Lojain O Almadfaa1, Abdulmoein E AlAgha1
1From the Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Saudi medical journal
|May 11, 2024
概括
在患有1型糖尿病 (T1DM) 的儿童中,糖尿病酸症 (DKA) 在中年儿童时期的男性中更为常见,并表现出季节性模式. DKA的严重程度与较低的经济地位,早期青春期和高血症有关.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 临床研究 临床研究
背景情况:
- 1型糖尿病 (T1DM) 是一种慢性疾病,需要谨慎管理.
- 糖尿病酸性糖尿病 (DKA) 是T1DM的一个严重并发症,特别是在儿童和青少年中.
- 了解DKA指标对于及时干预和改善患者结果至关重要.
研究的目的:
- 确定和评估与儿童T1DM患者DKA发作强度相关的临床指标.
- 探索影响DKA严重程度的人口,社会经济和临床因素.
主要方法:
- 从2018年至2022年,对156名患有DKA的儿科T1DM患者 (6个月至14岁) 进行了回顾性评估.
- 收集的数据包括人口统计,经济状况,临床表现,血糖控制,DKA严重程度和实验室结果.
- 统计分析以确定临床指标与DKA严重程度之间的相关性.
主要成果:
- 在中年男性中,DKA发作更频繁,并表现出季节性变化.
- DKA严重程度与经济状况相反,与青春期早期和新的T1DM诊断呈正相关.
- 低血糖控制,延长DKA持续时间,高血糖和特定的临床症状 (例如,意识下降,Kussmaul呼吸,脱水) 与严重的DKA有显著联系.
结论:
- 儿科T1DM中的DKA更多发生在中儿童时期的男性中,具有季节性模式.
- 经济地位较低,青春期早期和高血症等因素与DKA严重程度的增加有关.
- 临床指标和血糖控制对于评估和管理年轻T1DM患者的DKA强度至关重要.
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