在左心室辅助器件植入为目的地治疗的患者中驱动线感染
Grzegorz Wasilewski1, Sylwia Wiśniowska-Śmiałek1, Izabela Górkiewicz-Kot1
1Department of Cardiovascular Surgery and Transplantology, Jagiellonian University, Medical College, John Paul II Hospital, Cracow, Poland.
Transplantation proceedings
|May 11, 2024
概括
驱动线感染 (DLI) 是左心室辅助器件 (LVAD) 植入后的常见并发症. 更深的传动线放置和向的抗生素可以帮助优化这些感染的预防和治疗策略.
科学领域:
- 心血管外科心血管外科
- 医疗器械技术 医疗器械技术
- 传染性疾病 传染性疾病
背景情况:
- 由于供体器官短缺,对机械循环支持的需求日益增加.
- 左心室辅助器件 (LVAD) 是心脏移植的替代方案,用于末期心力衰竭.
- 驱动线感染 (DLI) 是LVAD植入后的常见并发症.
研究的目的:
- 分析LVADs患者的驱动线感染 (DLI) 流行病学.
- 调查植入技术对DLI率的影响.
- 确定优化DLI预防和治疗的策略.
主要方法:
- 在2015-2022年间接受LVAD植入 (Heartware HVAD,HeartMate 3) 的患者的回顾性分析.
- 纳入标准:至少12个月的随访时间.
- 收集关于患者人口统计,心脏状况,DLI发生,病原体和植入技术的数据.
主要成果:
- 在90名LVAD患者中,57%的患者至少经历过一次DLI,中位数在13个月开始.
- 对甲素敏感的金黄色葡萄球菌是最常见的病原体 (44%).
- 较深的驱动线植入 (直肠肌肉以下) 与较少的DLI和较长的DLI无间隔相关.
结论:
- 在LVAD植入后,DLI仍然是最常见的并发症.
- 最佳的手术技术,包括更深的传动线放置,对于预防DLI至关重要.
- 早期针对性抗生素治疗和仔细的患者选择对于改善LVAD结果至关重要.
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