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Updated: Jun 26, 2025

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
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通过USP7参与的分子粘剂对P53进行上调

Zhaoyang Li1, Ziying Wang1, Chao Zhong1

  • 1The State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Huashan Hospital, the Institutes of Brain Science, School of Life Sciences, Fudan University, Shanghai 200438, China.

Science bulletin
|May 11, 2024
PubMed
概括

研究人员确定了通过准USP7,一个二维基因酶来稳定P53蛋白的分子剂. 美国食品和药物管理局 (FDA) 批准的药物布罗莫克里普丁 (bromocriptine) 显示出显著的效果,抑制癌细胞增殖和瘤生长.

关键词:
消灭城市的消灭.在P53中,P53是P53USP7 USP7 美国提高监管 提高监管 提高监管

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