腹膜透析相关的腹膜炎:来自意大利中心长期分析的见解
Luca Nardelli1,2, Antonio Scalamogna3, Federico Ponzano3
1Division of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia. lcn.nardelli@gmail.com.
BMC nephrology
|May 11, 2024
概括
对腹膜透析 (PD) 腹膜炎的标准化定义对于临床实践至关重要. 应用ISPD 2022指南改善了与PD相关的腹膜炎结果的报告和分析.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内部医学 内部医学
- 临床研究 临床研究
背景情况:
- 腹膜炎是腹膜透析 (PD) 的严重并发症.
- 现有研究经常使用PD周周炎的各种定义和结果测量.
- 在ISPD 2022指南中,为腹膜炎提供了修订后的定义和结果指标.
研究的目的:
- 使用标准化ISPD 2022定义分析与PD相关的腹膜炎发作.
- 在PD患者队列中确定基线腹膜炎的发病率和结果.
- 强调在PD周周炎研究中标准化报告的重要性.
主要方法:
- 一项从2009年1月到2023年5月接受PD的267名患者的回顾性研究.
- 收集和分析所有与PD相关的腹膜炎发作.
- 应用ISPD 2022指南的定义和结果评估.
主要成果:
- 整体腹膜炎的发病率为0.25次/患者年,在一年内无腹膜炎生存率为84.2%.
- 医学治愈率为70.3%,耐火性周周炎为22.4%,培养负性周周炎为25.6%.
- 关键结局包括住院治疗 (64.4%),导管切除 (18.7%),血液透析转移 (18.3%) 和腹膜炎相关死亡 (6.8%).
结论:
- 标准化定义和结果测量对于PD炎研究至关重要.
- 一致的报告增强了临床实践,并促进了比较研究.
- "ISPD 2022指南"为改善PD周周炎的管理和研究提供了一个框架.
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