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V142I 变异的心血管负担

Senthil Selvaraj1,2, Brian Claggett3, Svati H Shah1,2

  • 1Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.

JAMA
|May 12, 2024
PubMed
概括

在黑人中,TTR V142I变体显著增加了心力衰竭 (HF) 和死亡风险. 这种变异与大量生命年数的丧失有关,强调了针对性治疗的必要性.

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