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Updated: Jun 26, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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CUX1通过BAF复合体调节人类造血干细胞染色质的可访问性

Weihan Liu1, Jeffrey L Kurkewich2, Angela Stoddart2

  • 1Department of Pathology, The University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA.

Cell reports
|May 12, 2024
PubMed
概括

转录因子CUX1充当先驱因子,指导染色体重塑复合体到DNA中,以调节血液细胞分化. 它缺乏干细胞有助于癌症的发展.

关键词:
在BAF复杂的 BAF复杂.科普:分子生物学 分子生物学科普:干细胞研究在 CUX1 的位置上,可以看到 CUX1 的位置.染色体改造器 染色体改造器不同化的差异化差异化.增强剂是一种增强剂.表观遗传调节 表观遗传调节造血干细胞 造血干细胞骨髓状瘤是什么样子的开拓者因素是开拓者因素.转录因子的转录因子

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