通过SCF-E3结合酶子单元FBXO24对FOXK2的向,用于调节线粒体呼吸的乌比奎介导降解

Rabab El-Mergawy1, Lexie Chafin1, Jose A Ovando-Ricardez1

  • 1Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.

概括

转录因子FOXK2在细菌性肺炎期间降解,影响线粒体功能. 抑制其降解可以保护线粒体的健康,从而揭示出一种新的调节机制.

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