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营养评估工具 (PNI,CONUT,GNRI) 可以预测脊柱手术后的不良事件吗? 一个系统的审查和元分析

Zhi Huang¹, Hanbo Wang¹, Yifeng Da¹

¹The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.

Journal of orthopaedic surgery and research

|May 12, 2024

概括

预后营养指数 (PNI) 和老年营养风险指数 (GNRI) 预测脊柱手术患者的不良事件. 控制营养状况 (CONUT) 显示了一个不显著的趋势. 这些营养标志物有助于评估外科手术风险.

科学领域:

手术瘤学手术瘤学
营养科学营养科学
临床结果研究研究

背景情况:

营养评估对于预测癌症患者的结果至关重要.
脊柱手术患者的营养指数的预测价值仍然不清楚.
本综述研究了预后营养指数 (PNI),控制营养状态 (CONUT) 和老年营养风险指数 (GNRI) 以预测脊柱手术中的不良事件.

研究的目的:

评估PNI,CONUT和GNRI在预测脊柱手术后不良事件中的实用性.
评估这些营养指数与手术部位感染 (SSI) 和死亡率的关联.

主要方法:

在PubMed,CENTRAL,Scopus和Embase数据库中进行了系统的文献搜索.
两位独立审查员选了截至2024年1月26日发表的研究.
使用元分析和聚合分析来综合总体不良事件,SSI和死亡率的数据.

主要成果:

在分析中包括了14项研究.
减少PNI显著与更高的不良事件风险相关,但不是SSI.
低GNRI与SSI和不良事件的风险增加有关;高CONUT显示了增加并发症的非显著趋势.

结论:

在脊椎外科手术中,PNI和GNRI是不利结果的有价值的预测指标.
高GNRI预测SSI的风险增加.
虽然CONUT显示与不良结果的关联不显著,但关于死亡率的数据仍然不足以得出最终的结论.

关键词:

控制营养状况控制营养状况老年人的营养风险指数.营养指数营养指数脊柱外科手术脊柱外科手术这是一个元分析.

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