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Updated: Jun 26, 2025

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通过TPR-CHAT对CRISPR-Cas7-11进行负调节的结构基础

Tian Hong1, Qinghua Luo1,2, Haiyun Ma1

  • 1Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.

Signal transduction and targeted therapy
|May 12, 2024
PubMed
概括

该CRISPR-Cas7-11RNA编辑工具由TPR-CHAT进行调节. TPR-CHAT的N终端域抑制了Cas7-11的活动,提高了CRISPR系统的安全性.

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