化学转移成像和扩散权重图像/显微扩散系数地图的实用性作为评估固体瘤的工具
Sahil Sharma1, Rekha Gupta2, Vidur Bhalla3
1Senior Resident, Department of Radiodiagnosis, PGI Chandigarh, Chandigarh, India, Corresponding Author.
概括
化学转移成像 (CSI) 和扩散加权成像 (DWI) /明显扩散系数 (ADC) 地图对于分类固体瘤是不可靠的. 血管肌脂瘤和乳头细胞癌中的微观脂肪限制了CSI.
科学领域:
- 放射学 放射学是指放射学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 磁共振成像 (MRI) 为CT提供了一个无辐射的替代方案,用于质量表征,具有卓越的软组织对比度.
- 对于患有慢性病的患者以及CT检测结果不确的患者来说,MRI特别有利.
- 扩散权重成像 (DWI) 在表征固体病变方面表现有前途,特别是当加多对比度是禁忌时.
研究的目的:
- 评估化学转移成像 (CSI) 和DWI/明显扩散系数 (ADC) 地图在评估固体瘤的诊断实用性.
- 确定CSI是否可以可靠地区分血管肌脂瘤 (AML) 和清细胞细胞癌 (ccRCC).
- 评估DWI/ADC地图在瘤组织学分类方面的潜力.
主要方法:
- 一项涉及24名患有固体质的患者的横截面研究.
- 所有患者都在1.5T使用干线圈进行了腹部上部MRI.
- 分析包括使用CSI和DWI/ADC映射技术.
主要成果:
- 在ADC值和瘤组织学亚型之间没有发现显著的关联 (p=0.082).
- 在50%的AML,40%的ccRCC和66%的 papillary RCC病例中观察到DWI的信号下降.
- 在AML和乳头RCC中,CSI发现了微观脂肪,使区分与ccRCC复杂化.
结论:
- CSI不是诊断ccRCC的可靠标志物,因为微观脂肪也存在于AML和 papillary RCC中.
- 仅使用DWI/ADC成像无法可靠地实现脏瘤的组织学分类.
- 可能需要进一步的研究来完善先进的MRI技术在脏瘤表征中的作用.
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