视频会议提供的小组认知行为压力管理ME/CFS患者出现严重PEM:一个随机对照试验
Marcella May1, Sara F Milrad2, Dolores M Perdomo1
1University of Miami.
Fatigue : biomedicine, health & behavior
|May 13, 2024
概括
通过视频会议进行的认知行为压力管理 (CBSM) 显著改善了肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 患者的症状和压力. 这种虚拟干预在这个患者群体中减少了PEM严重程度和症状负担.
科学领域:
- 医学研究 医学研究
- 心理学 心理学 心理学
- 慢性疾病管理 慢性疾病管理
背景情况:
- 运动后的不适 (PEM) 加剧了肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 的痛苦和症状.
- 认知行为压力管理 (CBSM) 显示出减轻与压力相关的PEM触发器的承诺.
- 研究了虚拟交付CBSM (V-CBSM),以提高ME/CFS患者的可访问性.
研究的目的:
- 评估虚拟CBSM干预对经历严重PEM的ME/CFS患者的压力和症状的影响.
- 评估V-CBSM与健康信息控制相比在管理PEM和相关症状方面的有效性.
- 确定V-CBSM是否影响PEM状态的长期分类.
主要方法:
- 一项随机对照试验将10周的V-CBSM (n=75) 与ME/CFS患者的虚拟健康信息 (V-HI) 控制 (n=75) 进行了比较.
- 参与者按基线PEM严重程度分层 (高PEM与低PEM).
- 线性回归和后勤回归分析了治疗对症状频率/强度,压力,疲劳和PEM状态的影响在5个月的随访期间,控制共变量.
主要成果:
- 在高PEM患者中,V-CBSM对降低症状频率,强度和疲劳干扰/强度产生了中大效应.
- 在接受V-CBSM (p=.07) 的高PEM患者中观察到感知压力的趋势下降.
- 在随访时,V-CBSM显示了降低高PEM分类风险的趋势 (p=.058).
结论:
- 虚拟CBSM对患有严重PEM的ME/CFS患者有好处.
- 随着时间的推移,V-CBSM可以有效地减少PEM的表达和严重程度.
- 这种干预表明,它有可能改善ME/CFS患者的生命质量,这些患者有显著的PEM.
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