使用感官引导的隔离方法发现了Allspice (Pimenta dioica) 中的苦味掩饰化合物
Jin-Pyo An1, Xin Liu1, Yu Wang1
1Department of Food Science and Human Nutrition, Citrus Research & Education Center, University of Florida, 700 Experiment Station Road, Lake Alfred, FL 33850, USA.
Food chemistry: X
|May 13, 2024
概括
来自的新型化合物可以掩盖功能性食品中的苦味. 这一发现可能通过通过TAS2R14受体减少苦味感知来增加有益营养药的消费.
科学领域:
- 食品科学 食品科学 食品科学
- 感官科学 感官科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 功能性食品中的苦味化合物提供健康益处,但减少了消费者接受.
- 苦味感知是由TAS2Rs (味道和嗅觉受体家族2) 介导的,特别是TAS2R14.
- 识别苦味掩饰剂是改善营养丰富食品和饮料可口性的关键.
研究的目的:
- 发现和描述可以掩盖功能性食品中苦味的化合物.
- 为了研究从所有香料中分离出来的化合物的苦味掩饰潜力.
- 在分子水平上阐明苦味掩饰活动的机制.
主要方法:
- 香料提取物的感觉指导分成.
- 使用核磁共振 (NMR) 和高分辨率质谱法 (HR-MS) 阐明结构.
- 在实验室中对与因相比的分离化合物的感觉评估.
- 分子对接分析针对TAS2R14痛苦受体.
主要成果:
- 五个单一的化合物被隔离和结构性地从 allspice 中识别出来.
- 化合物1在感官测试中表现出对因的显著苦味掩盖活性.
- 分子对接建议化合物1作为TAS2R14受体的对手.
结论:
- 化合物1,从中分离出来,具有苦味掩饰的特性.
- 这种化合物可以通过减轻苦味来增强功能性食品的消费.
- 与TAS2R14的相互作用为苦味调节提供了潜在的机制.
关键词:
(2R) -3- ((4-基-3-甲基-) -1,2-二醇 (PubChem CID: 101154580) 的使用情况.(4R) -R-terpineol 8-O-β-D-(6-O-galloyl) 葡萄皮化物 (PubChem CID: 10695593) 的使用情况苦味受体是苦味的受体之一.苦是一种苦.食物的味道 食物的味道皮门托尔 (PubChem CID: 9917512), (4S) -R-特尔皮诺尔 8-O-β-D-(6-O-加洛伊尔) 葡萄皮化物 (PubChem CID: 10552230) 的使用情况.斯法勒化物A (PubChem CID: 101702475) 是一种这就是TAS2R.味道调制器的调制器相关概念视频
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