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位于肉质候选基因中的SNP标记物之间的关联研究,具有肌脂肪含量,在危的双重用途牛群中

Kathrin Halli¹, Sven König¹, Isabella J Giambra¹

¹Institute of Animal Breeding and Genetics, Justus-Liebig-University, 35390 Giessen, Germany.

Translational animal science

|May 13, 2024

概括

这项研究将Rotes Höhenvieh牛的特定基因变异与肌肉内脂肪 (IMF) 含量联系起来. 研究结果表明,需要特定品种的遗传策略来优化肉类质量特征.

科学领域:

动物遗传学动物遗传学
肉类科学肉科学
量化遗传学量化遗传学

背景情况:

肌肉内脂肪 (IMF) 含量是肉质的关键指标.
识别与IMF相关的遗传标记可以帮助繁殖计划.
由于其广泛的IMF范围,Rotes Höhenvieh (RHV) 牛品种具有优质肉类生产的潜力.

研究的目的:

研究候选基因中的单核酸多态 (SNPs) 与RHV牛中的IMF含量之间的关联.
分析对IMF的等位基因替代和主导作用.
探索影响IMF的特定品种遗传特征.

主要方法:

542 RHV牛的表型为IMF的内容.
在候选基因中使用聚合酶连锁反应-限制片段长度多态性对六个SNP进行基因定型.
协会对动物的完整数据集和减少的数据集进行分析,具有高的IMF.

主要成果:

与视网膜酸受体相关的孤儿受体C (RORC) 基因在完整数据集中显示出与IMF的最强相关性 (P=0.075).
在减少的数据集中,甲状腺蛋白 (TG) 基因的g.422C>T SNP显著影响了IMF (P<0.05),基因型CT显示了最高的IMF.
在缩小数据集中的选择性基因型定型放大了基因型效应差异和主导值.

结论:

在RHV牛中,RORC和TG的遗传变异影响IMF.
为了优化肉类质量,需要RHV品种特定的遗传策略.
聚焦于适应的RHV的繁殖史可能解释了观察到的遗传特征.

关键词:

有双重用途的牛.肌肉内脂肪含量肌肉内脂肪含量肉质基因肉质基因肉质基因单个核酸的多态性.

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