左心室质量下降与缩症相关,老年住院患者的严重程度
Yang Liu1, Ling Li1, Hui Gong1
1Department of Geriatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, CN.
目标:
骨骼肌质量和心脏结构随年龄增长而变化。目前尚不清楚骨骼肌质量(SMM)的减少是否伴随心脏质量的下降。本研究旨在探讨老年住院患者中左心室质量(LVM)与肌少症及其严重程度之间的关系。
方法:
本研究共纳入71名肌少症受试者和103名非肌少症对照者。采用生物电阻抗分析、握力测试和5次起坐测试分别评估骨骼肌质量(SMM)、肌肉力量和身体功能。通过超声心动图评估心肌结构和功能。肌少症的诊断依据2019年亚洲肌少症工作组标准。
结果:
肌少症患者的左心室尺寸和左心室质量(LVM)均小于非肌少症对照组。重度肌少症患者的左心室尺寸和LVM均小于非重度肌少症患者。在单变量回归分析中,体重指数(BMI)、心脏大小和LVM与骨骼肌质量(SMM)或骨骼肌指数(SMI)呈正相关。在多变量回归分析中,BMI和LVM与SMM和SMI独立相关。LVM与BMI联合检测预测肌少症的敏感性为66.0%,特异性为88.7%(AUC:0.825;95% CI:(0.761, 0.889));p< 0.001。
结论:
在住院的老年患者中,左心室质量降低与肌肉减少症及其严重程度相关,而左心室质量与体重指数的联合检测对肌肉减少症具有预测价值。
更多相关视频
04:00Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
相关概念视频
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
