双极性障碍和精神分裂症的低肺功能:一种隐藏的风险
Cristina Ruiz-Rull1,2, María José Jaén-Moreno1,3, Gloria Isabel Del Pozo1,4
1Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.
Frontiers in physiology
|May 13, 2024
概括
患有严重精神疾病 (SMI) 的人显示肺功能显著受损,有较高的异常螺旋计图案率. 解决吸烟和肥胖等风险因素对这一群体至关重要.
科学领域:
- 肺部医学 肺部医学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 严重精神疾病 (SMI) 与增加的发病率和死亡率有关.
- 肺功能障碍是一般人群患病和死亡的已知风险因素.
研究的目的:
- 为了比较有SMI和没有SMI的个体之间的肺功能.
- 为了确定特定的螺旋测量模式和SMI相关的风险因素.
主要方法:
- 一项涉及287名年龄在40至70岁的成年人的横截面研究.
- 参与者包括患有精神分裂症或双相情感障碍的人和没有精神病诊断的对照人.
- 螺旋测量根据美国胸腔学会/欧洲呼吸学会标准进行.
主要成果:
- 与对照组相比,患有SMI的个体表现出较低的螺旋计值.
- 在SMI组中,异常的螺旋测量模式更频繁 (36.1% vs 16.9%).
- 在SMI组中,保留比率损伤螺旋测量 (PRISm) 和空气流阻塞模式显著更高,与腹周和吸烟相关,分别.
结论:
- 很大一部分SMI患者的肺功能受损.
- 定期的肺功能监测和可修改的风险因素 (吸烟,肥胖) 的管理对于SMI人口至关重要.
相关概念视频
Bipolar Disorder
67
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
67
Psychological and Sociocultural Causes of Schizophrenia
84
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
84
Biological Causes of Schizophrenia
55
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
55
Mania and Antimanic Drugs: Overview
174
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
174
Negative and Cognitive Symptoms of Schizophrenia
48
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
48
Schizophrenia
76
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
76


