刺激性肠综合征中的小纤维神经病变
Pouria Motaghi1,2, Iman Adibi2,3, Peyman Adibi4
1School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
小纤维神经病变 (SFN) 在刺激性肠综合征 (IBS) 患者中比健康个体更为普遍. 这表明IBS和SFN之间存在潜在联系,需要进一步调查和评估IBS患者的神经病变症状.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 临床医学 临床医学
背景情况:
- 小纤维神经病变 (SFN) 涉及小神经纤维的退化,导致像和麻木这样的感觉障碍.
- 此前,SFN与各种并发症有关,包括纤维肌痛和炎症性肠病.
研究的目的:
- 为了评估小纤维神经病变 (SFN) 的发生在被诊断患有刺激性肠综合征 (IBS) 的患者中.
主要方法:
- 一项横截面研究比较了42名IBS患者和43名健康对照者,使用密歇根神经病查仪器 (MNSI) 和犹他州早期神经病变量表 (UENS).
- 神经传导研究 (NCS) 对参与者进行了积极的查结果,以确认SFN诊断.
主要成果:
- 七名IBS患者 (16.7%) 和三名健康对照人 (6.9%) 查神经病变呈阳性.
- 根据检查和正常的NCS,四名IBS患者被诊断为SFN;没有一个健康对照被诊断为SFN.
- 在IBS和健康组之间观察到SFN患病率的统计学上显著差异 (p<0.05).
结论:
- SFN和IBS的同时发生表明IBS患者的潜在泛性神经病症综合征.
- 通过及时诊断和治疗,评估IBS患者对SFN的外围神经病变症状可能会改善患者的生活质量.
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