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与SARS-CoV-2感染相关的透析参数和末期脏疾病的预后
Rodrigo Bezerra1,2, Audes D M Feitosa2, Odilson M Silvestre3
1Keizo Asami Institute, Federal University of Pernambuco, Recife, PE, Brazil.
Annals of medicine
|May 13, 2024
概括
在急性COVID-19疾病期间,透析前血压的增加与末期病 (ESKD) 患者的更糟糕结果有关. 接种Covid-19疫苗与这些患者住院风险降低有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- COVID-19大流行严重影响了末期病 (ESKD) 的患者.
- 在COVID-19阳性ESKD患者中透析参数的预后价值此前尚不清楚.
研究的目的:
- 为了评估临床特征,血压 (BP) 和透析参数在ESKD患者和没有COVID-19的患者.
- 确定透析参数与COVID-19阳性ESKD患者的住院和死亡率等结果之间的关联.
主要方法:
- 来自巴西四个血液透析设施的107名Covid-ESKD和107名匹配的No-Covid-ESKD患者的回顾性评估.
- 在感染前,急性感染和感染后期间分析血压和透析参数.
- 主要结果包括COVID-19住院和全因死亡率,使用多变量后勤和Cox回归模型进行分析.
主要成果:
- 与疾病前相比,Covid-ESKD患者在急性疾病期间表现出增加的内透析和透析后心血压,以及降低了透析前体重,透析后体重,超率和间透析体重增加.
- 从疾病前期到急性疾病和Covid-19疫苗接种的预透析缩血压增加与Covid-ESKD患者的住院治疗有关.
- 与Covid-19相关的住院治疗和年龄较大是Covid-ESKD患者全因死亡率的独立预测因素.
结论:
- 急性Covid-19疾病改变了ESKD患者体积状况相关的透析参数.
- 在急性COVID-19感染期间升高的透析前血压与ESKD患者的不良预后有关.
- 接种Covid-19疫苗可能会降低ESKD患者住院的风险.
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