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Updated: Jun 26, 2025

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells
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Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells

Published on: May 16, 2017

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反感RNA C9orf72 六核酸重复与肌缩性侧面硬化症和前性痴呆症相关,形成三重体状结构,并结合小型合成连接体

Leszek Błaszczyk1, Marcin Ryczek1, Bimolendu Das2

  • 1Institute of Bioorganic Chemistry, Polish Academy of Sciences, Z. Noskowskiego 12/14, 61-704, Poland.

Nucleic acids research
|May 13, 2024
PubMed
概括

在C9orf72中六核酸重复 (HR) 的异常扩张导致ALS/FTD. 我们确定了带有和没有ANP77连接体的HRRNA的晶体结构,揭示了其三重结构和用于治疗设计的相互作用.

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RNA Structure01:19

RNA Structure

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