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Updated: Jun 30, 2026

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视觉化氧化瓜核酸积在活细胞与分裂的MutTT

Yoshihiro Fujikawa1, Hidehiko Kawai1, Tetsuya Suzuki1

  • 1Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

Nucleic acids research
|May 13, 2024
PubMed
概括

研究人员开发了一种新的方法来可视化活细胞中有毒的8-oxo-dGTP,帮助癌症研究. 该系统可以检测氧化应激,并可选MTH1抑制剂,潜在的抗癌药物.

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相关概念视频

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
In vitro Mutagenesis01:16

In vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.