在急性缺血性中风患者的再综合征的风险因素和结果
Shumin Chen1, Dongchun Cai1, Yuzheng Lai1
1Department of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Traditional Chinese University of Guangzhou, Foshan, China.
概括
再养综合征影响14.8%的急性缺血性中风患者,营养不良和中风严重程度是关键风险因素. 这种情况会使患者的结果恶化,并增加死亡风险.
科学领域:
- 神经学 神经学
- 临床营养学 临床营养学
- 临界护理医学 临界护理医学
背景情况:
- 急性缺血性中风患者通常需要营养支持,因为吞困难和意识变化.
- 重新养综合征 (RS) 是这些患者的一个风险,其特点是营养康复期间的电解质转移.
- 了解RS发病率和中风风险因素对于改善患者管理至关重要.
研究的目的:
- 为了确定在接受肠道营养的急性缺血性中风患者中重新养综合征的发生率.
- 确定与再养综合征发展相关的独立风险因素.
- 评估再综合征对中风患者结果的影响.
主要方法:
- 使用前性中风数据库进行回顾性观察性研究.
- 包括连续急性缺血性中风患者,接受肠道营养超过72小时.
- 重新养综合征定义为新发的低酸血症在养后72小时内;用于分析的后勤回归.
主要成果:
- 在338名患者中,有50名患者 (14.8%) 患上了再养综合征.
- 风险因素包括NIH中风量表得分较高,2002年营养风险查得分较高,白蛋白低 (<30 g/L),BMI低 (<18.5 kg/m2).
- 重新养综合征独立与3个月功能结果较差 (mRS>2) 和6个月死亡率增加相关.
结论:
- 重新养综合征是急性缺血性中风患者的常见并发症.
- 基线中风的严重程度,营养状况和低BMI都是重新养综合征的重要预测因素.
- 重新养综合征的存在与不良的临床结果和更高的死亡率有关.
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