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超重/肥胖的功能性改变:专注于奖励和执行控制网络
Haoyu Guo1,2, Jinfeng Han1,2, Mingyue Xiao1,2
1Faculty of Psychology, 26463 Southwest University , Chongqing, China.
Reviews in the neurosciences
|May 13, 2024
概括
超重和肥胖与大脑网络功能障碍有关,特别是奖励网络 (RN) 和执行控制网络 (ECN). 这些神经变化解释了对食物奖励的敏感性增加和超重/肥胖个体的饮食抑制.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 医学科学 医学科学 医学科学
背景情况:
- 超重 (OW) 和肥胖 (OB) 是全球重要的健康问题,增加了慢性疾病的风险.
- 它们给个人和社会带来了相当大的身体,精神,医疗和经济负担.
- 了解OW/OB的神经基础对于开发有效的干预措施至关重要.
研究的目的:
- 审查超重/肥胖的功能性大脑网络变化.
- 专注于奖励网络 (RN) 和执行控制网络 (ECN).
- 为未来的研究提出一种奖励抑制双系统模型.
主要方法:
- 分析和组织休息状态和基于任务的fMRI研究.
- 检查功能性大脑网络在超重/肥胖中的变化.
- 综合发现,以支持理论模型.
主要成果:
- 在RN和ECN的功能障碍是超重/肥胖的关键.
- 这些网络中的异常有助于增加食物奖励敏感性和进食失禁.
- 有证据支持在休息和任务条件下改变这些网络中的功能连接.
结论:
- 奖励和执行控制网络在超重/肥胖的病理生理学中发挥着关键作用.
- 奖励抑制双系统模型为了解超重/肥胖患者的饮食行为提供了一个框架.
- 需要进一步的研究来探索这种模式及其对治疗的影响.
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