[对于复发性直肠癌的治疗策略]
Sophia Dietz1,2, Johannes Fritzmann1,2, Anne Weidlich2,3
1Klinik und Poliklinik für Viszeral‑, Thorax- und Gefäßchirurgie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.
多式疗法显著降低局部晚期直肠癌的复发率. 然而,一些患者仍然经历局部复发,需要个性化手术来治疗潜在的治疗.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 辐射疗法 辐射疗法
背景情况:
- 新辅助性放射治疗和化疗之后的手术 (全腹腔切除) 改善了局部晚期直肠癌的结果.
- 尽管取得了进展,局部复发仍然是一个挑战,在多达10%的患者中发生.
研究的目的:
- 突出局部复发性直肠癌 (LRRC) 的挑战和个性化治疗策略.
- 强调手术R0切除对LRRC治疗意图的重要性.
主要方法:
- 对局部晚期和复发性直肠癌的多式疗法概念的审查.
- 讨论个性化治疗计划,考虑改变的骨盆解剖和复发特征.
主要成果:
- 多种模式的方法已经大大降低了直肠癌的复发率.
- 手术R0切除对于在LRRC中实现治愈至关重要.
- 复杂的案例,包括那些与相邻结构参与的案例,可以通过多式联运概念来管理.
结论:
- 对LRRC的治疗决定需要由跨学科团队仔细个性化.
- 即使在晚期病例中,LRRC的潜在治愈治疗也可以在专门的中心实现.
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