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奥菲奥博林A对线粒体复合体IV有共性向,导致癌细胞的代谢崩

Flor A Gowans1,2,3,4,5, Danny Q Thach2,3, Zhouyang Zhu2,3

  • 1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, California 94720, United States.

ACS chemical biology
|May 13, 2024
PubMed
概括

奥菲奥博林A (OPA) 是一种抗癌化合物,向线粒体复合体IV蛋白COX5A和HIGD2A. 这会扰乱细胞的能量产生,导致癌细胞通过受损的线粒体能量死亡.

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