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Updated: Jun 26, 2025

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在小鼠肝脏中,FicD调节了对未折叠蛋白质反应的适应

Amanda K Casey1, Nathan M Stewart1, Naqi Zaidi2

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA; Howard Hughes Medical Institute, Dallas, TX, 75390, USA.

Biochimie
|May 13, 2024
PubMed
概括

酶FicD在生理压力期间调节未折叠蛋白反应 (UPR). 虽然缺乏FicD的肝脏组织表现出弹性,但它适应重复的压力,表明组织在UPR调节中的特定作用.

关键词:
在AMPylation的过程中,AMPylation的细胞内膜网膜应激 (ER应激) 的压力肝脏新陈代谢 肝脏的新陈代谢鼠标 鼠标是一个鼠标.不折叠的蛋白质反应 (UPR)

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