更高的饮食中聚醇摄入量与较低的血液炎症标记物有关
Elliot R Dryer-Beers1, Jennifer Griffin2, Paul M Matthews3
1Nutrition and Dietetics Research Group, Imperial College London, London, United Kingdom; UK Dementia Research Institute and Department of Brain Sciences, Imperial College London, London, United Kingdom.
The Journal of nutrition
|May 13, 2024
概括
饮食中多的摄入量较高与降低了诸如C反应蛋白 (CRP) 和纤维素原 (fibrinogen) 等炎症标志物有关. 这项针对英国大群体的研究支持了食品和饮料中发现的多的健康益处.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 流行病学 流行病学
背景情况:
- 饮食中的多与较低的慢性疾病风险有关,可能通过减少氧化应激和炎症.
- 评估聚醇摄入量与炎症之间的联系是具有挑战性的,因为在大量人群中对两者的数据有限.
研究的目的:
- 为了研究聚醇摄入量与血液中炎症生物标志物之间的关联.
- 为了评估英国的Airwave队列中的多醇消费模式.
主要方法:
- 一项对来自英国Airwave队列的9008名参与者 (17-74岁) 的横截面分析.
- 通过使用7天的饮食日记和Phenol-Explorer数据库来估计多的摄入量.
- 用C反应蛋白 (CRP) 和纤维素素作为系统性炎症的血液生物标志物.
主要成果:
- 总共有448种多被确定,其中酸和黄酸是最常见的.
- 较高的每日聚醇总摄入量显示出与CRP (P < 0.001) 和纤维素原 (P = 0.038) 的反向关联.
- 增加的聚醇摄入量与CRP升高的几率降低有关,在四分位数中观察到显著的逐步减少.
结论:
- 这项研究量化了英国大型队列中多的摄入量,揭示了较高摄入量和较低水平的炎症标志物之间的显著关联.
- 这些发现有助于证据基础支持饮食中的多在人类健康中的有益作用.
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