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Updated: Jun 26, 2025

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压力介导的多酸盐20降解及其对治疗蛋白的潜在影响

Baikuntha Aryal1, Mari Lehtimaki1, V Ashutosh Rao2

  • 1Laboratory of Applied Biochemistry, Division of Biotechnology Research and Review III, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administrations, Silver Spring, MD, 20993, USA.

Pharmaceutical research
|May 13, 2024
PubMed
概括

聚酸二氧化物20 (PS20) 的降解,受脂肪酸含量,酶,pH和温度的影响,产生自由脂肪酸和颗粒. 在我们的研究中,这些降解产品并没有显著影响治疗蛋白质的质量或稳定性.

关键词:
聚酸盐是一种多酸盐.生物活动是生物活动.埃斯特拉酶的使用方法自由脂肪酸是一种自由的脂肪酸.脂酶脂酶的使用方法

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