我们应该使用哪个参考方程来解释澳大利亚原住民的螺旋测量值? 一个横截面研究.
Andrew J Collaro1,2, Rachel Foong3,4, Anne B Chang1,5
1Queensland Hospital and Health Service, Brisbane, QLD.
The Medical journal of Australia
|May 14, 2024
概括
新的参考方程显示,澳大利亚原住民的正常肺功能更高. GLI-2022和GLI-2012方程适用于评估这个人群的呼吸能力.
科学领域:
- 肺部医学 肺部医学
- 土著健康研究土著健康研究
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 精确评估呼吸能力对于诊断和管理肺部疾病至关重要.
- 现有的参考方程可能无法充分代表像澳大利亚原住民这样多样化的人口的肺功能.
- 全球肺功能倡议 (GLI) 提供了广泛使用的螺旋计参考方程.
研究的目的:
- 评估GLI-2012其他/混合和GLI-2022全球参考方程的适用性,以评估澳大利亚原住民的呼吸能力.
- 为了比较健康的第一民族个人队伍中这些方程的表现.
主要方法:
- 一项横截面研究分析了来自昆士兰州,北领地和西澳大利亚州进行的三项前性研究的螺旋测量数据.
- 包括2015年3月至2022年12月期间招募的1467名健康的第一民族参与者 (儿童和成人) 的数据.
- 用GLI-2012和GLI-2022方程的平均Z分数和标准偏差来评估合适度的良好程度.
主要成果:
- 无论是GLI-2012其他/混合方程还是GLI-2022全球方程,都表明它们与螺旋计数据相匹配.
- GLI-2022的种族中立方程更好地解释了年龄和身高对第一秒强制呼气量 (FEV1) 和强制生命能力 (FVC) 的影响.
- 与城市参与者相比,农村/偏远地区的参与者在使用GLI-2012方程时,平均FEV1和FVC Z-score较低,但FEV1/FVC Z-score较高.
结论:
- 对于健康的澳大利亚第一民族人来说,正常的螺旋计值可能高于以前报告的值.
- GLI-2022全球和GLI-2012其他/混合参考方程适用于评估澳大利亚第一民族人的呼吸功能.
- 对于更精细的参考值,需要从城市第一民族人口中获得进一步的螺旋测量数据.
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