在口腔膜复合癌中下侵袭的临床,放射和病理相关性
Subinsha A1, Rupa Mehta1, Nitin M Nagarkar1
1Department of Otorhinolaryngology-Head and Neck Surgery, AIIMS, Raipur, Chhattisgarh India.
Indian journal of surgical oncology
|May 14, 2024
概括
临床评估对于检测口腔癌下部侵袭的高度敏感. 虽然CT扫描提供了100%的灵敏度,但MRI更好地将瘤大小与组织病理学相关联,有助于对口腔 - 气泡综合体癌症的治疗计划.
科学领域:
- 口腔瘤学 在口腔瘤学.
- 医学成像医学成像
- 手术病理学的外科病理学
背景情况:
- 嘴膜复合体的癌症经常涉及下,使治疗和预后复杂化.
- 准确评估下部侵袭对于手术规划和瘤结果至关重要.
- 目前的诊断方法在精确确定骨透的程度方面存在局限性.
研究的目的:
- 关联临床,放射学和病理学发现,以 mandibular 侵袭在口腔癌.
- 在检测下部侵袭时,评估骨造影,CT扫描和MRI的灵敏度和特异性.
- 为了比较术前的评估与术后的组织病理学结果.
主要方法:
- 64名经过活检证明的口腔癌患者的前性横截面研究.
- 在手术前临床和放射性评估下关节干扰.
- 临床放射学发现与切除标本的组织病理学分析的比较.
主要成果:
- 在男性中,口腔癌的患病率是男性的四倍;18%的病例显示骨入侵.
- 临床评估表明,对下部侵袭有很高的敏感性.
- CT扫描的灵敏度为100% (特异性为46%),MRI灵敏度为54.5% (特异性为96%) 和Orthopantomogram灵敏度为66.6% (特异性为100%).
- 核磁共振扫描显示,瘤大小与组织病理学有很好的相关性;瘤分化和入侵之间存在反向关系.
- 性癌症没有显示下入侵;临床T和N阶段与他的病理学有显著的相关性.
结论:
- 临床评估是口腔癌下部侵袭的敏感预测指标.
- CT和MRI,与临床评估一起,是评估下部侵袭的有价值的补充工具.
- 准确测量骨侵袭仍然具有挑战性,需要综合诊断方法.
- 再生医学的进步为骨缺陷重建提供了未来的可能性.
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