胃食道逆流症和喘控制的关系
Arzoe Singh1, Rahul Khanna2, Annya Suman3
1College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA.
European clinical respiratory journal
|May 14, 2024
概括
胃食道逆流症 (GERD) 显著降低了喘控制测试 (ACT) 的得分,可能误导了喘控制. 除了ACT,FEV1%和FeNO等客观测量对于准确的喘评估至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 胃肠病学 胃肠病学
- 临床医学 临床医学
背景情况:
- 喘控制通常使用喘控制测试 (ACT) 进行评估.
- 胃食道逆流性疾病 (GERD) 是喘患者常见的并发症.
- GERD对喘控制感知的影响需要进一步研究.
研究的目的:
- 为了确定GERD是否混了喘患者的ACT分数.
- 为了评估ACT得分与客观肺功能测量 (FEV1%和FeNO) 在GERD存在时的一致性.
主要方法:
- 一项前性队列研究,涉及307名喘患者.
- 数据收集包括人口统计,ACT评分,FEV1%测量和FeNO测试.
- 根据GERD的存在或不存在来对患者进行分类.
主要成果:
- 与没有GERD的患者相比,患有GERD的患者的ACT平均得分明显较低 (p < .001).
- 这种差异在不同的喘控制水平中持续存在,GERD患者无论FEV1%或FeNO水平,都显示出较低的ACT得分.
- 具体来说,控制不良的患有GERD的喘患者的ACT分数较低 (p < .001对于FEV1%,p = .008对于FeNO),以及控制良好的喘患者 (p < .001对于FEV1%和FeNO).
结论:
- GERD症状可能导致主观低估通过ACT控制喘.
- 在患有GERD的患者中,ACT评分可能不准确地反映客观肺功能 (FEV1%,FeNO).
- 将客观措施与ACT整合起来至关重要,以防止GERD患者的喘管理不当.
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