埃塞俄比亚门诊机构的抗生素适用性:需要一个抗生素管理计划
Rahel Belete Abebe1, Bezawit Mulat Ayal2, Muluken Adela Alemu3
1Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Drugs in context
|May 14, 2024
概括
在埃塞俄比亚,近一半的门诊抗生素处方是不合适的,特别是对于肺炎和胃潰瘍疾病. 这凸显了对抗生素管理的迫切需要,以打击耐药性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗生素耐药性是一个主要的全球健康威胁,由过度和不适当的抗生素使用驱动.
- 据估计,全球约有50%的抗生素处方是不适当的.
- 这项研究调查了埃塞俄比亚门诊护理中的抗生素处方模式.
研究的目的:
- 评估埃塞俄比亚的门诊护理访问中不适当的抗生素处方的流行情况.
- 为了确定在门诊环境中不适当的抗生素处方的模式.
主要方法:
- 使用定量方法进行了基于设施的横截面研究.
- 从Debre Markos专科综合医院 (2022年5月-6月) 的门诊患者的处方被随机选择.
- 用描述性统计和推断性测试 (基平方,t测试) 来分析数据,p<0.05被认为是显著的.
主要成果:
- 在分析的911份处方中,49.5%不符合国家治疗指南.
- 在社区获得的肺炎 (38.8%与30.1%) 和胃潰瘍疾病 (14.9%与9%) 中,违规率明显高.
- 不恰当的处方更频繁地发生在阿莫西西林/克劳兰酸 (48.2%) 和塞法列辛 (24.3%) 身上.
结论:
- 埃塞俄比亚的大量门诊抗生素处方不符合国家指导方针.
- 处方者在为门诊患者开处方抗生素 (如阿莫西西林/克劳兰酸和塞法莱克辛) 时需要提高注意力.
- 实施抗生素管理计划对于优化门诊抗生素使用和减轻埃塞俄比亚不适当的处方至关重要.
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