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Updated: Jun 26, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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通过SID1识别双链RNA的结构基础

Runhao Wang1, Ye Cong2, Dandan Qian1

  • 1State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin 300350, China.

Nucleic acids research
|May 14, 2024
PubMed
概括

研究人员阐明了系统性RNAi缺陷 (SID) 1蛋白与双链RNA (dsRNA) 结合的结构. 这揭示了SID1如何识别和结合dRNA,这对于基于RNA的疗法至关重要.

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