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相关概念视频

Hair Cells01:22

Hair Cells

Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...

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相关实验视频

Updated: Jun 18, 2026

Cochlear Implantation in the Guinea Pig
09:56

Cochlear Implantation in the Guinea Pig

Published on: June 15, 2018

11.2K

在微猪中插入电极阵列后,听力功能和内内形态的变化.

Haiqiao Du1,2,3,4,5, Jianan Li1,2,3,4,5, Zhifeng Chen1,2,3,4,5,6

  • 1Senior Department of Otolaryngology-Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.

Acta oto-laryngologica
|May 14, 2024
PubMed
概括
此摘要是机器生成的。

耳电极插入显著影响听力,并导致耳内纤维化和内淋巴体水. 这些变化在手术后四周内没有影响螺旋结神经元.

关键词:
电极阵列插入插入器耳植入器是什么意思异物体的反应反应迷你猪 迷你猪 迷你猪

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The Miniature Pig: A Large Animal Model for Cochlear Implant Research
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相关实验视频

Last Updated: Jun 18, 2026

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09:56

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Published on: June 15, 2018

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The Miniature Pig: A Large Animal Model for Cochlear Implant Research
06:16

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Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
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科学领域:

  • 耳鼻喉科 耳鼻喉科 耳鼻喉科
  • 神经科学是一个神经科学.
  • 生物材料科学是生物材料的科学.

背景情况:

  • 在长期使用耳植入物的人的骨中观察到异物反应.
  • 耳纤维化的进展及其对植入后听力的影响仍然不清楚.

研究的目的:

  • 为了研究在微猪中插入电极阵列后,听力和耳组织病理学的短期变化.
  • 了解耳植入物对听觉功能和内耳环境的动态影响.

主要方法:

  • 十二只小猪接受了电极阵列插入 (EAI);用于比较,使用了对照组.
  • 听力测试进行了手术前和手术后的0,7,14,28天.
  • 在手术后的7,14,28天评估了耳组织病理学.

主要成果:

  • 插入电极阵列显著影响了1kHz-20kHz频率范围内的听力.
  • 插入后一周观察到脱皮,四周后形成纤维.
  • 总是发现内淋巴体液体,但螺旋性结节神经元形态和密度保持不变.

结论:

  • 插入电极阵列显著影响听力,并导致内纤维化.
  • 纤维化和内淋巴水与听力损失严重程度没有相关性.
  • 在手术后四周,螺旋质神经元的完整性得到保护,这表明神经系统的潜在保存.