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快速分类一种新的导致ALS的I149S变体在超氧化物脱酶-1中

Victoria K Shephard1, Mikayla L Brown1, Bryony A Thompson2

  • 1Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia.

Amyotrophic lateral sclerosis & frontotemporal degeneration
|May 14, 2024
PubMed
概括

一种新的超氧化物脱酶-1 (SOD1) 变体,I149S,与肌缩性侧面硬化症 (ALS) 有关. 这种SOD1变异导致蛋白质不稳定和聚合,将其重新归类为可能引起ALS的病原体.

关键词:
在SOD1中,SOD1是SOD1.变体分类的变体分类

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