分析阳三元组:发现预防老年人受伤的策略
Vinodkumar Mugada1, Srinivasa Rao Yarguntla2, Satya Sai Srinivas Allada1
1Vignan Institute of Pharmaceutical Technology, Department of Pharmacy Practice, Duvvada, India.
Turkish journal of pharmaceutical sciences
|May 14, 2024
概括
这项研究发现,药物复杂性,潜在不合适的药物 (PIM) 和药物相互作用在老年患者中很常见. 互动,协作和教育等策略可以防止这种催产素三位一体.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
背景情况:
- 催产素三位一体,包括潜在不合适的药物 (PIM),多药和药物相互作用,对老年人群构成重大健康风险.
- 评估和缓解这个三位一体对于改善老年患者的健康结果至关重要.
研究的目的:
- 为了评估在门诊老年患者中阳性三元体的患病率.
- 在这个人口群体中确定对iatrogenic三位一体的潜在预防措施.
主要方法:
- 一项初步的观察性研究,涉及150名老年患者.
- 使用了AGS Beers标准2019,多药学评估和药物复杂性疗法指数 (MRCI).
- 使用Micromedex软件评估药物相互作用.
主要成果:
- 观察到中等程度的药物治疗方案复杂性 (MRCI: 30.49 ± 13.77).
- 格利梅皮里德和迪克洛芬雅是最常见的PIM;中度的药物相互作用被注意到 (例如,阿司匹林/美托普罗罗尔).
- MRCI和多药与PIM和药物相互作用有显著的相关性 (p < 0.01).
结论:
- 药物治疗方案的复杂性,PIM和药物相互作用是老年患者普遍存在的问题.
- 确定的预防策略包括加强互动,医疗保健提供者之间的合作和持续教育.
- 实施这些策略可以减少伤害,提高老年患者的护理质量.
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