相关实验视频
Updated: Jun 26, 2025

08:56
Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
9.1K
与COVID-19 ICU幸存者的疲劳相关的因素
Djahid Kennouche1, Clément Foschia2, Callum G Brownstein1
1Université Jean Monnet Saint-Etienne, Inter-university Laboratory of Human Movement Biology, Saint-Etienne, FRANCE.
Medicine and science in sports and exercise
|May 14, 2024
概括
重症监护室 (ICU) 后的COVID-19患者经常会感到疲劳,这与呼吸功能低下和神经肌肉变化有关. 康复对于恢复和改善这些幸存者的生活质量至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 住院治疗COVID-19,特别是在重症监护室 (ICU),影响了很大一部分感染者.
- 治疗后ICU疲劳是COVID-19幸存者的普遍和持续症状,影响他们的康复和生活质量.
研究的目的:
- 调查COVID-19 ICU住院治疗后患者持续疲劳的相关因素.
- 确定生理和患者报告的结果,以区分疲劳和非疲劳的COVID-19幸存者.
主要方法:
- 59名COVID-19 ICU幸存者接受了评估,包括问卷,血液采样,心肺运动测试和神经肌肉功能评估.
- 评估是在出院后大约52天进行的,一周后进行了神经肌肉评估的子集.
主要成果:
- 56%的患者使用FACIT-F问卷报告疲劳.
- 与非疲劳患者相比,疲劳患者的肺功能 (强迫生命能力) 显著降低,最大自愿激活率较低.
- 患者报告的结果显示,两组人之间睡眠,体力活动,抑郁和生活质量存在显著差异.
结论:
- COVID-19幸存者在出院4-8周后表现出持续的呼吸功能障碍和神经肌肉变化,疲劳加剧了这些问题.
- 在这一群体中,疲劳与自愿肌肉活化减少以及睡眠,情绪和生活质量受损有关.
- 运动干预和康复对于治疗ICU后COVID-19患者的心肺呼吸系统和神经肌肉缺陷至关重要,特别是那些经历疲劳的人.
相关概念视频
Fatigue
181
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
181
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
Muscle Recovery and Fatigue
2.1K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.1K
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
COPD: Pathogenesis and Clinical Features
263
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
263
Factors Affecting Pulmonary Ventilation
1.3K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.3K

