性驱动因素与自身免疫性糖尿病中的焦虑和抑郁有关
Enrico Saudelli1,2, Simona Moscatiello1, Michele Baldari1,2
1Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Acta diabetologica
|May 14, 2024
概括
焦虑影响了近三分之一的患有自身免疫糖尿病的成年人,而抑郁影响了十分之一. 这些心理健康状况与可改变的因素有关,并且在性别之间存在差异,这突显了需要量身定制的干预措施的需要.
科学领域:
- 内分泌学和新陈代谢学
- 精神病学和心理健康 精神病学和心理健康
- 糖尿病研究 糖尿病研究
背景情况:
- 自免疫性糖尿病,包括1型糖尿病和成年人的潜伏性自身免疫性糖尿病,对患者的福祉提出了独特的挑战.
- 焦虑和抑郁是慢性疾病中的重要并发症,可能会影响疾病管理和生活质量.
研究的目的:
- 在被诊断患有自身免疫糖尿病的大量成年人中确定焦虑和抑郁症的患病率.
- 在这个患者群体中确定与焦虑和抑郁相关的性别特异因素.
主要方法:
- 一项涉及434名患有自身免疫性糖尿病的成年人的横截面研究,他们参加了第二剂SARS-CoV-2疫苗接种.
- 使用了经过验证的问卷,包括医院焦虑和抑郁量表,糖尿病痛苦量表等.
- 在四个月内收集的临床,生化和葡萄糖监测数据 (如有).
主要成果:
- 焦虑和抑郁的患病率分别为30.4%和10.8%.
- 与糖尿病相关的更高的情绪负担和更低的治疗满意度是这两种情况的风险因素.
- 女性的性别与焦虑有关;抑郁症的风险因素因性别而异,与女性的年龄和男性的HbA1c有关.
结论:
- 很大一部分患有自身免疫性糖尿病的人会经历焦虑和抑郁.
- 这些心理健康状况与可修改和不可修改的患者特征有关.
- 导致抑郁症的具体因素在患有自身免疫糖尿病的男性和女性患者之间有很大差异.
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