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Updated: Jun 26, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

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机器学习的自适应性工作流程阐明了TAK1的Allosteric网络的顺序操作机制

Nibedita Ray Chaudhuri1, Shubhra Ghosh Dastidar1

  • 1Biological Sciences, Bose Institute, EN 80, Sector V, Bidhan Nagar, Kolkata 700091, India.

Biochemistry
|May 14, 2024
PubMed
概括

机器学习算法揭示了通过TAB1.1.驱动TAK1激活的关键残留相互作用. 这项研究增强了对全性机制的理解,并为药物发现确定了新的热点.

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