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Updated: Jun 26, 2025

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通过近距离标记确定的SRSF1互动体揭示了与拼接体RNA基酶DDX23的直接相互作用

Danilo Segovia1,2, Dexter W Adams3,4,5, Nickolas Hoffman1

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.

Proceedings of the National Academy of Sciences of the United States of America
|May 14, 2024
PubMed
概括

通过近距离标记来绘制SRSF1蛋白相互作用,确定了190种蛋白质. 一个关键的发现是SRSF1和DDX23之间的验证相互作用,对于mRNA前拼接调节至关重要.

关键词:
在DDX23和DDX23之间.这种SR蛋白质是SR蛋白质.在SRSF1中,我们可以使用SRSF1.在mRNA前拼接.接近性标签的标签.

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